Anastrozole Powder Dosage

1. For men:
Anastrozole has been tested for reducing estrogens, including estradiol, in men. Excess estradiol in men can cause benign prostatic hyperplasia, gynecomastia, and symptoms of hypogonadism. It can also contribute to increased risk of stroke, heart attack, chronic inflammation, prostate enlargement and prostate cancer.
Some athletes and body builders use anastrozole as part of their steroid cycle to reduce and prevent symptoms of excess estrogen–gynecomastia, emotional lability and water retention. Study data suggests dosages of 0.5 mg to 1 mg a day reduce serum estradiol approx. 50% in men, which differs in postmenopausal women.

2. For children:
Anastrozole may be used off-label in children with precocious puberty, or children with pubertal gynecomastia.Following the onset of puberty, the epiphyseal plate begins to close due to an increased amount of estrogen production escaping local metabolism and spreading to the circulatory system.

It is shown to help slow this process, and increase adult height prediction in adolescent males treated with protein-based peptide hormones for the treatment of growth hormone deficiency.

Anastrozole Powder COA
Items Standard Results
Description White crystalline powder Complies
Identification IR Conform with standard IR
HPLC Conform with standard HPLC
Reactive Conform
Solubility Freely soluble in methanol, Complies
acetone,ethanol and tetrahydrofuran.
And very soluble in acetonitrile
Total Impurity max.0.5% 0.18%
Total Unspecified Impurity max. 0.2% 0.08%
Individual unspecified impurlty max. 0.1% 0.05%
Related compound B max. 0.2% 0.07%
Related compound C max. 0.2% 0.04%
Related compound D max. 0.1% 0.05%
Related compound E max. 0.1% 0.06%
Limit of cyclohexane max. 0.08% ND
Limit of ethylacetate max. 0.1% 0.07%
Melting point 81.0~84.0ºC 82.5~83.2ºC
Water max. 0.3% 0.21%
Residue on ignition max. 0.1% 0.07%
Heavy Metals max.0.001% Complies
Assay(HPLC) 98.0%~102.0% 99.30%
Storage Cool and dry
Conclusion It complies to USP32 .