Raloxifene Hydrochloride Powder Quick Detail:
Product name: Raloxifene hydrochloride
Other name: Raloxifene HCL;KEOXIFENE;AKOS 92138
Possible similar drugs: Evista; Evista
CAS register number: 82640-04-8
Steroid Class: Anti Estrogen Steroids
Appearance: Light yellow powder
Molecular formula: C28H28ClNO4S
Molecular weight: 510.04
Melting point: 250-253°C
Treatment for: the treatment/prevention of osteoporosis and reduction of breast cancer riskinpostmenopausalwomen.
Storage: Shading, confined preservation
Raloxifene Hydrochloride Powder Description:
Raloxifene hydrochlorideis an estrogen agonist/antagonist, commonly referred to as a selective estrogen receptor modulator (SERM) that belongs to the benzothiophene class of compounds. Raloxifene hydrochloride (HCl) has the empirical formula C28H27NO4SHCl, which corresponds to a molecular weight of 510.05. Raloxifene HCl is an off-white to pale yellow solid that is very slightly soluble in water.
Raloxifene Hydrochloride Powder Applications:
Raloxifene hydrochloridei is supplied in a tablet dosage form for oral administration. Each EVISTA tablet contains 60 mg of raloxifene HCl, which is the molar equivalent of 55.71 mg of free base. Inactive ingredients include anhydrous lactose, carnauba wax, crospovidone, FD&C Blue No. 2 aluminum lake, hypromellose, lactose monohydrate, magnesium stearate, modified pharmaceutical glaze, polyethylene glycol, polysorbate 80, povidone, propylene glycol, and titanium dioxide.
Raloxifene Hydrochloride Powder Specifications:
|Appearance||White &off-white powder||Conform|
|Solubility||Soluble in 10% sodium hydroxide solution. Slightly Soluble in methanol. Insoluble in water||Conform|
|Tests||Loss on drying||≤0.5%||0.4%|
|Residue on ignition||≤0.1%||0.06%|
|RRelated substances||Raloxifene Impurity1||≤0.20 %||0.10%|
|Any unspecified individual impurity 2||≤0.10%||Max. 0.08%|
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