Dextromethorphan Hydrobromide Quick Detail:
Alias: Dextromethorphan Hbr, Dextromethorphan Hydrobromicum, Dextromethorphan Hydrobromide, Romilar
CAS No.: 125-69-9
EINECS No.: 204-750-1
Appearance: White or kind of white crystalline powder, soluble in water.
Usage: Hormones and Regulation of Endocrine Function of Drug
Dextromethorphan Hydrobromide Description:
DXM is also used recreationally. When exceeding label-specified maximum dosages, dextromethorphan acts as a dissociative hallucinogen. Its mechanism of action is via multiple effects, including actions as a nonselective serotonin reuptake inhibitor and a sigma-1 receptor agonist. The major metabolite of DXM, dextrorphan, also acts as an NMDA receptor antagonist. In high doses this produces effects similar to, yet distinct from, the dissociative states created by other dissociative anaesthetic. As well, the metabolite 3-methoxymorphinan of dextrorphan (thus a second-level metabolite of DXM) produces local anesthetic effects in rats with potency above dextrorphan, but below that of DXM.
Dextromethorphan Hydrobromide Applications:
Usage:Inhibit medullary cough center to produce antitussive effect. Normal therapeutic dose does not inhibit breathing, long-term use without addiction and tolerance.
Dextromethorphan (DXM or DM) is an antitussive (cough suppressant) drug.
Dextromethorphan has also found other uses in medicine, ranging from pain relief to psychological applications. It is sold in syrup, tablet, spray, and lozenge forms. In its pure form, dextromethorphan occurs as a white powder.
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