Product name: Liothyronine Sodium Powder
Alias: Cytomel T3; 3, 3′, 5-triiodothyronine sodium
CAS No.: 55-06-1
Molecular formula: C15H11I3NNaO4
Molecular weight: 672.96
Characters: White or light yellow powder, almost tasteless.
Use: It is suitable for various causes of hypothyroidism.
Packing: 1kg/aluminum foil bag.

Thyroid hormone drugs are natural or synthetic preparations containing tetraiodothyronine (T4, levothyroxine) sodium or triiodothyronine (T3, liothyronine) sodium or both. T4 and T3 are produced in the human thyroid gland by the iodination and coupling of the amino acid tyrosine. T4 contains four iodine atoms and is formed by the coupling of two molecules of diiodotyrosine (DIT). T3 contains three atoms of iodine and is formed by the coupling of one molecule of DIT with one molecule of monoiodotyrosine (MIT).

Liothyronine Sodium Powder COA
Item Specification Result
Appearance An odorless, almost white or buff colored powder pass
Solubility 1,Very slightly soluble in water pass
2,slightly soluble in alcohol pass
3,practically insoluble in most other organic solvents pass
4,disolves in diluted aqueous sodium hydroxide solutions Pass
Identificaton a) Heat about 50 mg with a few drops of sulfuric acid in a porcelain crucible: violet vapors of iodine are evolved. pass
b)The retention time of the major peak is confirm to the RS pass
Loss on Drying Not more than 4.0% 0.46%
 [a]20/D

C=1 in 1M HCl/EtOH 1:4

+18 ~ +22o +20.9o
Assay(HPLC) Not less than 95.0% 99.18%
Levothyroxine sodium Not more than 5.0% 0.68%
Conclusion: Up to the Standard for Export